Abstract: Scientific evidence has shown that natural disasters have severe short- and long-run impacts on economic growth, development, and poverty reduction. With climate change being recognized as one of the most significant challenges facing humankind in the 21st century, it is predicted to exacerbate climate hazards and amplify the risk of extreme weather disasters. People in the developing world are widely believed to be more vulnerable to natural disasters and climate change because of their reliance on agriculture, resource scarcity, poor infrastructure, and unstable institutions. The 2009 World Development Report found that by the end of this century, Vietnam will be one of five countries most affected by natural disasters and climate change due to its long coastlines, a high concentration of population and economic activity in coastal areas and a heavy reliance on agriculture, natural resources, and forestry. This chapter presents findings relating to the impacts of natural disasters and climate change on agriculture in Vietnam. In nearly all regions of the country, agricultural production is expected to decline. Rice production is found to be most affected by natural disasters climate change, while Central Highland and North-West are the most vulnerable regions.